General Western Blot Reagents
Abcam Chetomin, HIF signaling inhibitor, 5MG
MW 710.9 Da, Purity >98%. Potent HIF signaling inhibitor. Reduces CA9 and VEGF expression in hypoxic cells (IC₅₀ = 10 nM, secreted VEGF, Hep38 cells). Shows antibacterial and antifungal effects. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam VU0155041 sodium salt, PAM for mGluR4, 10MG
MW 338.2 Da, Purity >98%. Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is water soluble and more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Also available in simple stock solutions (ab146686) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam KN-62, CaM kinase II inhibitor. P2 x 7 antagonist., 1MG
MW 721.8 Da, Purity >98%. Cell-permeable, reversible and selective inhibitor of CaM kinase II (IC50 = 500 nM). Interacts with the calmodulin binding site of the enzyme. At higher concentrations reported to inhibit GSK3β, PRAK and MAPKAP-K2. Also potent non-competitive antagonist at the P2X7 receptor (IC50 = 15 nM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SIRT6 Activity Assay Kit (Fluorometric)
SIRT6 Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam BHHCT, Fluorescent sensitizer for Eu3+- labelling, 5MG
MW 804.9 Da, Purity >90%. Fluorescent sensitizer for Eu3+- labelling. Increases luminescence intensity 11 fold. Persists as an Eu3+ complex for 500 μs typical of the Eu3+ oxidation state. Measures peroxidase activity and oxidative stress levels.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NBQ x , AMPA / kainate antagonist, 50MG
MW 336.28 Da, Purity >99%. Potent, selective and competitive AMPA/kainate receptor antagonist. Neuroprotective and anticonvulsant in vivo. Water-soluble form available - please see NBQX disodium salt (ab120046).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PARK7/DJ1 peptide, 1MG
Human PARK7/DJ1 peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: Parkinson disease protein 7, Maillard deglycase, Oncogene DJ1, Parkinsonism-associated deglycase, Protein DJ-1, Protein/nucleic acid deglycase DJ-1, DJ-1, PARK7
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bezafibrate, Pan-PPAR agonist, 5G
MW 361.8 Da, Purity >99%. Pan-PPAR agonist (EC₅₀ values are 50, 60 and 20 μM at PPARα, PPARγ and PPARδ human receptors respectively). More efficient than fenofibrate (ab120832) in reducing body weight and blood glucose. Antidiabetic and antihyperlipidemic effects.
The product is subject to the following: Abcam Restricted Use Statement
![Abcam Anti-FOXA1 antibody [RM1119] - BSA and Azide free.](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502711400.JPG-250.jpg)
Abcam Anti-FOXA1 antibody [RM1119] - BSA and Azide free.
Anti-FOXA1 antibody [RM1119] - BSA and Azide free.
The product is subject to the following: Abcam Restricted Use Statement
Abcam D-Fructose 1,6-diphosphate trisodium salt, Common metabolic sugar, 5G
MW 406.06 g/mol, Purity >98%. Common metabolic sugar. Precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. Allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase. Inhibitor of acetate kinase. Used as a substrate to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1,6-bisphosphatase(s).
The product is subject to the following: Abcam Restricted Use Statement
Abcam BU 224 hydrochloride, Imidazoline I2 binding site allosteric modulator, 50MG
MW 233.69 Da, Purity >99%. High affinity Imidazoline I2 binding site allosteric modulator (Ki = 2.1 nM). Dose-dependently inhibits C-fiber evoked responses, post-discharge and wind-up. Shows antinociceptive effects *in vivo.*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Malate Dehydrogenase 2 (MDH2) Activity Assay
Malate Dehydrogenase 2 (MDH2) Activity Assay
The product is subject to the following: Abcam Restricted Use Statement
Abcam Anti Cd47 Antibody Rm1014 AB284132-1ML
Anti Cd47 Antibody Rm1014 AB284132-1ML
The product is subject to the following: Abcam Restricted Use Statement
Abcam BTBCT, Europium beta-diketone chelate, 250MG
MW 604.9 Da, Purity >95%. Europium β-diketone chelate. Provides 8 times improved detection sensitivity compared to BHHCT-(Asc5314
The product is subject to the following: Abcam Restricted Use Statement
Abcam Metronidazole, Antiparasitic and antibacterial compound, 5G
MW 171.15 Da, Purity >99%. Nitroimidazole compound with antiparasitic and antibacterial activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement